The E 450's turbocharged inline-six, the engine most owners upgrade for. Photo: Mercedes-Benz USA.
2026 Mercedes-Benz E 450: Brooklyn Buyers Guide
Quick Answer: 2026 Mercedes-Benz E 450
The E 450 4MATIC starts at $72,300 MSRP plus the $1,250 destination charge, and it's the E-Class most Brooklyn shoppers describe as the sweet spot. Its 3.0-liter turbo inline-six with mild-hybrid assist makes 375 horsepower and 369 lb-ft, standard 4MATIC all-wheel drive puts the power down, and Mercedes-Benz's own spec sheet lists 0-60 in 4.4 seconds. EPA fuel-economy certification lists 22 city / 31 highway / 25 combined mpg; note that mbusa.com's own model page shows a different figure (23/33), which we flag below rather than repeat as gospel. Everything standard on the E 350, the dual displays, wireless CarPlay, the driver-assistance suite, carries over unchanged.
The engine that changes the conversation
Where the E 350's four-cylinder is competent, the E 450's inline-six is the reason people specifically ask for it. The extra two cylinders bring 120 more horsepower and 74 more lb-ft over the 350, and the character difference is bigger than the numbers suggest: an inline-six turbo spins up with a smoothness a four-cylinder, however well engineered, doesn't quite match. 0-60 drops to 4.4 seconds, and the merge onto the Prospect Expressway stops being a calculation and starts being reflexive.
4MATIC is standard here, not optional, which settles the winter-traction debate the E 350 buyer still has to have. Every 2026 E 450 leaves the factory ready for a Brooklyn February.
A word on the fuel-economy number
Worth flagging plainly, because it's the kind of detail a buyer deserves straight: Mercedes-Benz's own E 450 model page lists 23 city / 33 highway mpg, but the EPA's official certification for the same vehicle shows 22 city / 31 highway / 25 combined. The two don't match, and when a manufacturer's own marketing page and the EPA's certified rating disagree, the EPA number is the one that governs the window sticker and the one we'd trust for real-world budgeting. Either way, expect the E 450 to trail the E 350 modestly at the pump in exchange for meaningfully quicker acceleration.
What buyers say about the six-cylinder cars
Vitaliy Sarkisyan's review from this July reads like a chase scene: "Great service from Mike and Naran. The guys did the impossible found me a car that was no longer available and gave me an amazing price and amazing service. Thank you guys!!!" Naran Biurchiev, credited by name, works in pre-owned acquisition and lease returns per the dealership's team page and turns up in more than one review for tracking down a specific configuration a buyer wanted. It is the kind of legwork that matters more on a six-cylinder car, where inventory turns faster than the four-cylinder volume seller.
Options worth actually specifying
The optional MBUX Superscreen Package, a second display for the front passenger layered onto the two already standard, is the headline add-on across the E-Class line, and it is genuinely useful on longer trips when a passenger wants their own navigation or media view. Beyond that, most E 450 buyers spec the car close to standard: the drivetrain is doing the differentiating work here, not the options list.
Frequently asked questions
How much is the 2026 E 450?
$72,300 MSRP plus $1,250 destination and New York taxes and fees. That's roughly $6,000 over a 4MATIC E 350 for 120 more horsepower and standard all-wheel drive. The pricing guide covers the full New York math.
What's the real fuel economy on the E 450?
The EPA-certified figure is 22 city / 31 highway / 25 combined mpg. Mercedes-Benz's own spec page lists 23/33, a discrepancy we'd rather point out than paper over; budget around the EPA number.
Does the E 450 come in rear-wheel drive?
No, 4MATIC all-wheel drive is standard on every 2026 E 450; there is no rear-drive configuration, unlike the E 350. For New York winters, that's a feature, not a limitation.
How does the E 450 compare to the AMG E 53 HYBRID?
The E 450 is quick (4.4 seconds to 60) and roughly $17,000 less; the AMG E 53 HYBRID is genuinely fast (3.9 seconds) and adds a plug-in battery with about 43 miles of electric range. Buyers who want six-cylinder character without the AMG premium, or a charging routine, generally land on the 450.
Where can I test drive an E 450 in Brooklyn?
At Mercedes-Benz of Brooklyn on Shore Parkway, off Belt Parkway Exit 5, with more than 500 vehicles typically in stock across the E-Class range.
The one most owners describe as "right"
Ask an E-Class owner which trim they'd buy again and the inline-six comes up disproportionately often; it is the point on the range where power stops being theoretical. Compare it against the entry car in the E 350 guide or the plug-in AMG in the AMG E 53 HYBRID guide before deciding, and check current numbers against the pricing and leasing guide.
MSRP figures exclude the $1,250 destination charge plus taxes, title, registration, and dealer-installed options; the dealer sets the actual selling price. Fuel-economy figures are EPA estimates and real-world results will differ; where the manufacturer's published figure and the EPA certification differ, the EPA figure is used. Equipment, packages, and availability can shift with configuration and production timing; confirm current specs with Mercedes-Benz of Brooklyn. Customer quotes are excerpts from public Google reviews of Mercedes-Benz of Brooklyn.